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Françoise Barré-Sinoussi

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Françoise Barré-Sinoussi
(July 30, 1947 - )
Born in France
Year of Discovery:
1983
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barre-sinoussi_crop_2008wikFirst to Isolate the AIDS Virus

In the early 1980s AIDS (acquired immunodeficiency syndrome) became one of the great unknowns in the world of medicine.  Finding the cause of this killer became a number one priority in labs all over the world.  Françoise Barré-Sinoussi was the scientist who first found the enzyme evidence of the virus responsible for this horrible disease.  Working with Luc Montagnier, her discovery led to the identification of HIV (human immunodeficiency virus) which was the first step in dealing with AIDS. 



Françoise Barré-Sinoussi was a retrovirus expert brought into the virology department at the Pastuer Institute in France.  She was born in Paris and educated there as well, graduating from Paris University of Sciences and receiving her Ph.D. in virology from the Institut Pasteur and University of Sciences.  She also did postdoctoral work at the National Institutes of Health in Bethesda, Maryland.  While working as an assistant professor at the Institut Pasteur, she began working with Luc Montagnier on trying to isolate a cause for AIDS.  They obtained a lymph node from a young AIDS patient and went to work.  Thinking the causative agent was a  retrovirus, Sinoussi measured an enzyme produced by retroviruses in the cell cultures they had set up with the lymph node.  At the time, there were only two known retroviruses.  Surprisingly, when they detected enzyme activity, they did not find either of the known retroviruses.  It was the elusive AIDS virus they had isolated.  After many more trials and experiments to prove they had found the causative agent they published their findings.  With the identification of the virus, work could begin to combat it.

Dr. Barré-Sinoussi has been very active in teaching others how to research as well as being active in many humanitarian organizations that look for solutions to the problem of AIDS.   In 2008, she was awarded the Nobel Prize in Medicine for her discovery along with Luc Montagnier.  To sum up her philosophy she said, “There is always hope in life, because there is always hope in science.”

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Introduction by Martha Pat Kinney


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Table of Contents

Introduction
Links to More Information About the Scientist
Key Insight
Key Experiment or Research
Key Contributors
Quotes by the Scientist
Quotes About the Scientist
Anecdotes
Fun Trivia About The Science
The Science Behind the Discovery
Personal Information
Science Discovery Timeline
Recommended Books About the Science
Books by the Scientist
Books About the Scientist
Awards
Major Academic Papers
Curriculum Vitae
Links to Science and Related Information on the Subject
Sources

 








Links to More About the Scientist & the Science

Wikipedia entry:
http://en.wikipedia.org/wiki/Fran%C3%A7oise_Barr%C3%A9-Sinoussi

Nobel Prize entry:
http://nobelprize.org/nobel_prizes/medicine/laureates/2008/barre-sinoussi-or.html

Women in Science, Nobel Announcement
http://sciencewomen.blogspot.com/2008/10/virologist-francoise-barre-sinoussi.html

Women in Technology International, Hall of Fame entry:
http://www.witi.com/center/witimuseum/halloffame/2006/fbarre-sinoussi.php

The American Association for the Advancement of Science article, "A History of HIV Discovery"
http://aidscience.org/science/298%285599%291727.html




i00923_1983
Barre-Sinoussi in 1983 - Image Copyright Institut Pasteur





Image Flow Here




Key Insight




Key Experiments or Research

 



Key Contributors

The Team
Explore other scientists who furthered this lifesaving advance.
Lifesavers: AIDS
Acquired Immune
Deficiency Syndrome
Luc Montagnier
Developed the blood test to detect HIV, the underlying cause of AIDS.
Gervais Dionne
Co-developed the effective AIDS drug 3TC, which had fewer side effects than AZT.
Bernard Belleau
Co-developed the effective AIDS drug 3TC, which had fewer side effects than AZT.
Francesco Bellini
Co-developed the effective AIDS drug 3TC, which had fewer side effects than AZT.
Nghe Nguyen-Ga
Co-developed the effective AIDS drug 3TC, which had fewer side effects than AZT.





Quotes by the Scientist




Quotes About the Scientist




Anecdotes




Fun Trivia About the Science




The Science Behind the Discovery



Personal Information



Scientific Discovery Timeline




Recommended Books About the Science




Books by the Scientist




Books About the Scientist

 



Awards




Major Academic Papers Written by the Scientist



Curriculum Vitae



Links to Information on the Science





Sources/References